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Thalidomide-O-amido-C6-NH2 TFA

CAS No. 1950635-14-9

Thalidomide-O-amido-C6-NH2 TFA( Cereblon Ligand-Linker Conjugates 11 TFA | E3 Ligase Ligand-Linker Conjugates 25 TFA | E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate | Thalidomide-O-amido-C6-NH2 TFA )

Catalog No. M26948 CAS No. 1950635-14-9

Thalidomide-O-amido-C6-NH2 TFA, a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 67 In Stock
5MG 38 In Stock
10MG 54 In Stock
25MG 88 In Stock
50MG 127 In Stock
100MG 230 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Thalidomide-O-amido-C6-NH2 TFA
  • Note
    Research use only, not for human use.
  • Brief Description
    Thalidomide-O-amido-C6-NH2 TFA, a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.
  • Description
    Thalidomide-O-amido-C6-NH2 TFA, a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    Cereblon Ligand-Linker Conjugates 11 TFA | E3 Ligase Ligand-Linker Conjugates 25 TFA | E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate | Thalidomide-O-amido-C6-NH2 TFA
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    DNA replication| HCMV| Nucleoside Analogue
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1950635-14-9
  • Formula Weight
    544.484
  • Molecular Formula
    C23H27F3N4O8
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (183.66 mM)
  • SMILES
    OC(=O)C(F)(F)F.NCCCCCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hamada A, et al. Clinical pharmacokinetics of cytarabine formulations.Clin Pharmacokinet. 2002;41(10):705-18.
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