Cart
sales@molnova.com
Thalidomide-O-amido-C6-NH2 TFA
CAS No. 1950635-14-9
Thalidomide-O-amido-C6-NH2 TFA( Cereblon Ligand-Linker Conjugates 11 TFA | E3 Ligase Ligand-Linker Conjugates 25 TFA | E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate | Thalidomide-O-amido-C6-NH2 TFA )
Catalog No. M26948 CAS No. 1950635-14-9
Thalidomide-O-amido-C6-NH2 TFA, a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 67 | In Stock |
|
| 5MG | 38 | In Stock |
|
| 10MG | 54 | In Stock |
|
| 25MG | 88 | In Stock |
|
| 50MG | 127 | In Stock |
|
| 100MG | 230 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameThalidomide-O-amido-C6-NH2 TFA
-
NoteResearch use only, not for human use.
-
Brief DescriptionThalidomide-O-amido-C6-NH2 TFA, a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.
-
DescriptionThalidomide-O-amido-C6-NH2 TFA, a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
In Vivo——
-
SynonymsCereblon Ligand-Linker Conjugates 11 TFA | E3 Ligase Ligand-Linker Conjugates 25 TFA | E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate | Thalidomide-O-amido-C6-NH2 TFA
-
PathwayOthers
-
TargetOther Targets
-
RecptorDNA replication| HCMV| Nucleoside Analogue
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1950635-14-9
-
Formula Weight544.484
-
Molecular FormulaC23H27F3N4O8
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (183.66 mM)
-
SMILESOC(=O)C(F)(F)F.NCCCCCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Hamada A, et al. Clinical pharmacokinetics of cytarabine formulations.Clin Pharmacokinet. 2002;41(10):705-18.
molnova catalog
related products
-
ABTS diammonium salt
ABTS diammonium salt is a substrate for horseradish peroxidase (HRP) conjugate.
-
GPDA
GPDA is a substrate of X-Prolyl dipeptidyl-aminopeptidase in the enzyme assay.
-
Terpinolene
Terpinolene shows non-genotoxic and antioxidant features. Terpinolene is a potent antiproliferative agent for brain tumour cells and may have potential as an anticancer agent.
