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VH032-cyclopropane-F
CAS No. 2306193-99-5
VH032-cyclopropane-F( VHL ligand 3 | E3 ligase Ligand 19 | Phenolic VH101 )
Catalog No. M26942 CAS No. 2306193-99-5
VH032-cyclopropane-F is a VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein by a linker to form PROTACs. PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 40 | In Stock |
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| 5MG | 33 | In Stock |
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| 10MG | 50 | In Stock |
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| 25MG | 87 | In Stock |
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| 50MG | 129 | In Stock |
|
| 100MG | 198 | In Stock |
|
| 200MG | 326 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameVH032-cyclopropane-F
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NoteResearch use only, not for human use.
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Brief DescriptionVH032-cyclopropane-F is a VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein by a linker to form PROTACs. PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4.
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DescriptionVH032-cyclopropane-F is a VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein by a linker to form PROTACs. PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4.
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In Vitro——
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In Vivo——
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SynonymsVHL ligand 3 | E3 ligase Ligand 19 | Phenolic VH101
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PathwayOthers
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TargetOther Targets
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RecptorRGS19| RGS4
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Research Area——
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Indication——
Chemical Information
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CAS Number2306193-99-5
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Formula Weight532.63
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Molecular FormulaC26H33FN4O5S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (187.75 mM)
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SMILESCc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(F)CC2)C(C)(C)C)c(O)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Blazer LL, et al. Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteins. Mol Pharmacol. 2010 Sep;78(3):524-33.
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