Biotin-PEG4-Amide-C6-Azide( —— )

Catalog No. M26907 CAS No. 1006592-62-6

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HNMR

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Product Name

Biotin-PEG4-Amide-C6-Azide
Note

Research use only, not for human use.
Brief Description

Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Description

Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

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Research Area

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Indication

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CAS Number

1006592-62-6
Formula Weight

615.79
Molecular Formula

C27H49N7O7S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (162.39 mM)
SMILES

[H][C@]12CS[C@@H](CCCCC(=O)NCCOCCOCCOCCOCCC(=O)NCCCCCCN=[N+]=[N-])[C@@]1([H])NC(=O)N2
Chemical Name

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1.D T Vo, et al. Insect nicotinic acetylcholine receptor agonists as flea adulticides in small animals. J Vet Pharmacol Ther. 2010 Aug;33(4):315-22.

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