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Biotin-PEG4-Amide-C6-Azide
CAS No. 1006592-62-6
Biotin-PEG4-Amide-C6-Azide( —— )
Catalog No. M26907 CAS No. 1006592-62-6
Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 71 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 48 | In Stock |
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| 10MG | 72 | In Stock |
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| 25MG | 121 | In Stock |
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| 50MG | 160 | In Stock |
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| 100MG | 237 | In Stock |
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| 200MG | 352 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameBiotin-PEG4-Amide-C6-Azide
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NoteResearch use only, not for human use.
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Brief DescriptionBiotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DescriptionBiotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number1006592-62-6
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Formula Weight615.79
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Molecular FormulaC27H49N7O7S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (162.39 mM)
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SMILES[H][C@]12CS[C@@H](CCCCC(=O)NCCOCCOCCOCCOCCC(=O)NCCCCCCN=[N+]=[N-])[C@@]1([H])NC(=O)N2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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NPAS3-IN-1
NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization, modulating NPAS3 transcription by targeting the interaction between NPAS3 and ARNT at the cellular level.
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IQB-782
IQB-782 is a mucolytic agent with mucolytic expectorant activity.IQB-782 inhibits thrombin-activating fibrinolytic inhibitor (TAFI), protects rats from tobacco smoke-induced respiratory obstruction.
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OD1
Potent rat Nav1.7, human Nav1.4 and rat Nav1.6 channel activator (EC50 values are 7, 10 and 47 nM, respectively). Exhibits minimal activation at mammalian Nav1.2, Nav1.3 and Nav1.5 (EC50 values >3 μM). Inhibits fast inactivation on all channels. Increases peak currents at all voltages and stimulates a persistent Na+ current at hNav1.7 channel. Increases hyperpolarization at Nav1.4 and Nav1.6 channels. Induces spontaneous pain in vivo.
