Azido-PEG12-NHS ester

CAS No. 2363756-50-5

Azido-PEG12-NHS ester( —— )

Catalog No. M26894 CAS No. 2363756-50-5

Azido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 74 In Stock
10MG 107 In Stock
25MG 176 In Stock
50MG 254 In Stock
100MG 362 In Stock
200MG 444 In Stock
500MG 727 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Azido-PEG12-NHS ester
  • Note
    Research use only, not for human use.
  • Brief Description
    Azido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • Description
    Azido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Ole1| Stearoyl-CoA Desaturase (SCD)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2363756-50-5
  • Formula Weight
    740.801
  • Molecular Formula
    C31H56N4O16
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Vincent BM, et al. Inhibiting Stearoyl-CoA Desaturase Ameliorates α-Synuclein Cytotoxicity. Cell Rep. 2018 Dec 4;25(10):2742-2754.e31.
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