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Amino-PEG12-amine
CAS No. 361543-12-6
Amino-PEG12-amine( H2N-PEG12-CH2CH2NH2 | PEODA13 )
Catalog No. M26883 CAS No. 361543-12-6
Amino-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameAmino-PEG12-amine
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NoteResearch use only, not for human use.
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Brief DescriptionAmino-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DescriptionAmino-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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SynonymsH2N-PEG12-CH2CH2NH2 | PEODA13
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PathwayOthers
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TargetOther Targets
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RecptorAntimalarial
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Research Area——
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Indication——
Chemical Information
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CAS Number361543-12-6
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Formula Weight588.736
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Molecular FormulaC26H56N2O12
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Purity>98% (HPLC)
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Solubility——
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SMILESNCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Taft BR, et, al. Discovery and Preclinical Pharmacology of INE963, a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncomplicated Malaria. J Med Chem. 2022 Mar 10;65(5):3798-3813.
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