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Amino-PEG12-alcohol
CAS No. 1345681-71-1
Amino-PEG12-alcohol( —— )
Catalog No. M26882 CAS No. 1345681-71-1
Amino-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 33 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameAmino-PEG12-alcohol
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NoteResearch use only, not for human use.
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Brief DescriptionAmino-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DescriptionAmino-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorTLR7| TLR8
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Research Area——
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Indication——
Chemical Information
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CAS Number1345681-71-1
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Formula Weight545.667
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Molecular FormulaC24H51NO12
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Purity>98% (HPLC)
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Solubility——
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SMILESNCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Jaromir Vlach, et al. Discovery of M5049: A Novel Selective TLR7/8 Inhibitor for Treatment of Autoimmunity. J Pharmacol Exp Ther. 2020 Dec 16;JPET-AR-2020-000275.
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