Pomalidomide-PEG4-C-COOH

CAS No. 2097938-44-6

Pomalidomide-PEG4-C-COOH( Cereblon Ligand -Linker Conjugates 1 | E3 Ligase Ligand-Linker Conjugates 1 )

Catalog No. M26874 CAS No. 2097938-44-6

Pomalidomide-PEG4-C-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 83 In Stock
5MG 61 In Stock
10MG 93 In Stock
25MG 170 In Stock
50MG 245 In Stock
100MG 346 In Stock
200MG 510 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Pomalidomide-PEG4-C-COOH
  • Note
    Research use only, not for human use.
  • Brief Description
    Pomalidomide-PEG4-C-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
  • Description
    Pomalidomide-PEG4-C-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Cereblon Ligand -Linker Conjugates 1 | E3 Ligase Ligand-Linker Conjugates 1
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    V-domain Ig suppressor of T-cell activation (VISTA)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2097938-44-6
  • Formula Weight
    507.496
  • Molecular Formula
    C23H29N3O10
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (98.52 mM)
  • SMILES
    OC(=O)COCCOCCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gabr MT, Gambhir SS. Discovery and Optimization of Small-Molecule Ligands for V-Domain Ig Suppressor of T-Cell Activation (VISTA). J Am Chem Soc. 2020 Sep 23;142(38):16194-16198.
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