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SJ572403
CAS No. 19970-45-7
SJ572403( SJ403 )
Catalog No. M26819 CAS No. 19970-45-7
SJ572403 is an inhibitor of disordered protein p27.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 87 | In Stock |
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| 5MG | 79 | In Stock |
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| 10MG | 122 | In Stock |
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| 25MG | 244 | In Stock |
|
| 50MG | 384 | In Stock |
|
| 100MG | 555 | In Stock |
|
| 200MG | 733 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSJ572403
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NoteResearch use only, not for human use.
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Brief DescriptionSJ572403 is an inhibitor of disordered protein p27.
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DescriptionSJ572403 is an inhibitor of disordered protein p27.(In Vitro):SJ572403 (10 μM-3 mM) replaces p27-D2 on Cdk2/cyclin A and partially restores Cdk2 kinase activity. SJ572403 (0-3 mM) modulates Cdk regulation of p27.
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In VitroSJ572403 (SJ403) (3 mM) shows specific interactions with specific regions within the D2 subdomain of p27-KID with a Kd value of 2.2 mM.SJ572403 (0-3 mM) modulates p27's Cdk regulatory.SJ572403 (10 μM-3 mM) displaces p27-D2 from Cdk2/cyclin A and partially restores Cdk2 kinase activity.
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In Vivo——
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SynonymsSJ403
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PathwayOthers
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TargetOther Targets
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RecptorHIV-1
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Research Area——
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Indication——
Chemical Information
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CAS Number19970-45-7
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Formula Weight275.312
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Molecular FormulaC13H17N5O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 13.89 mg/mL (50.45 mM)
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SMILESCCn1c(C)c(C)n2c1nc1n(C)c(=O)n(C)c(=O)c21
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kortagere S, et al. Structure-activity relationships of a novel capsid targeted inhibitor of HIV-1 replication. J Chem Inf Model. 2014 Nov 24;54(11):3080-90.
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