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RU-302
CAS No. 1182129-77-6
RU-302( [2-[(3,5-dimethyl-1,2-oxazol-4-yl)methylsulfanyl]phenyl]-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone )
Catalog No. M26815 CAS No. 1182129-77-6
RU-302 is a pan inhibitor of TAM Receptor blocking the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 79 | Get Quote |
|
| 5MG | 132 | Get Quote |
|
| 10MG | 230 | Get Quote |
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| 25MG | 410 | Get Quote |
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| 50MG | 605 | Get Quote |
|
| 100MG | 860 | Get Quote |
|
| 500MG | 1728 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameRU-302
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NoteResearch use only, not for human use.
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Brief DescriptionRU-302 is a pan inhibitor of TAM Receptor blocking the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain.
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DescriptionRU-302 is a pan inhibitor of TAM Receptor blocking the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain. RU-302 effectively blocks the activation of Gas6-inducible AXL and suppresses lung cancer tumor growth.
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In Vitro——
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In Vivo——
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Synonyms[2-[(3,5-dimethyl-1,2-oxazol-4-yl)methylsulfanyl]phenyl]-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone
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PathwayTyrosine Kinase
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TargetTAM Receptor
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Recptorneuropeptide S receptor (NPSR)
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Research Area——
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Indication——
Chemical Information
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CAS Number1182129-77-6
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Formula Weight475.53
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Molecular FormulaC24H24F3N3O2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (210.29 mM)
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SMILESCc1noc(C)c1CSc1ccccc1C(=O)N1CCN(CC1)c1cccc(c1)C(F)(F)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Batran RZ, et al. New quinolone derivatives as neuropeptide S receptor antagonists: Design, synthesis, homology modeling, dynamic simulations and modulation of Gq/Gs signaling pathways. Bioorg Chem. 2021;111:104817.
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