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Radezolid
CAS No. 869884-78-6
Radezolid( RX-1741 )
Catalog No. M26804 CAS No. 869884-78-6
Radezolid is a novel oxazolidinone antibiotic agent.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 120 | In Stock |
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| 5MG | 107 | In Stock |
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| 10MG | 187 | In Stock |
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| 25MG | 339 | In Stock |
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| 50MG | 514 | In Stock |
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| 100MG | 733 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRadezolid
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NoteResearch use only, not for human use.
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Brief DescriptionRadezolid is a novel oxazolidinone antibiotic agent.
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DescriptionRadezolid is a novel oxazolidinone antibiotic agent.(In Vitro):Radezolid displays a greater potency than linezolid, independent of the bacteria tested, when concentrations are expressed on a weight (mg/L) basis. Radezolid shows an improved potency compared to that of linezolid when concentrations are expressed on a weight (mg/L) basis. Radezolid MICs are systematically equal to or lower (up to 3 log2 dilutions) than those of linezolid for all linezolid-susceptible strains, with an 8-fold difference for the linezolid-resistant strains. Radezolid and TR-700 perform well against 3-copy G2447T, G2576T, and G2576T/T2571C mutants .
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In VitroRadezolid MICs are systematically equal to or lower (up to 3 log2 dilutions) than those of linezolid for all linezolid-susceptible strains, with an 8-fold difference for the linezolid-resistant strains. Radezolid shows a greater potency than linezolid, independent of the bacteria tested, when concentrations are expressed on a weight (mg/L) basis. Radezolid shows an improved potency compared to that of linezolid when concentrations are expressed on a weight (mg/L) basis. Radezolid and TR-700 perform well against 3-copy G2447T, G2576T, and G2576T/T2571C mutants.
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In Vivo——
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SynonymsRX-1741
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorTNIK
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Research Area——
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Indication——
Chemical Information
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CAS Number869884-78-6
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Formula Weight438.463
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Molecular FormulaC22H23FN6O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 25 mg/mL (57.02 mM)
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SMILESCC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(c(F)c1)-c1ccc(CNCc2cnn[nH]2)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Lee Y, et al. Synergistic inhibition effect of TNIK inhibitor KY-05009 and receptor tyrosine kinase inhibitor dovitinib on IL-6-induced proliferation and Wnt signaling pathway in human multiple myeloma cells. Oncotarget. 2017 Jun 20;8(25):41091-41101.
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