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Pranidipine
CAS No. 99522-79-9
Pranidipine( OPC-13340 )
Catalog No. M26794 CAS No. 99522-79-9
Pranidipine is a novel, long-acting 1,4-dihydropyridine calcium channel blocker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 67 | In Stock |
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| 2MG | 38 | In Stock |
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| 5MG | 61 | In Stock |
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| 10MG | 93 | In Stock |
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| 25MG | 198 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NamePranidipine
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NoteResearch use only, not for human use.
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Brief DescriptionPranidipine is a novel, long-acting 1,4-dihydropyridine calcium channel blocker.
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DescriptionPranidipine is a novel, long-acting 1,4-dihydropyridine calcium channel blocker. It prolongs acetylcholine-induced relaxation in presence of endothelium as well as nitroglycerin-induced relaxation in absence of endothelium. It also has antihypertensive activity.(In Vivo):Pranidipine enhances cyclic GMP-dependent nitric oxide-induced relaxation of rat aorta.
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In Vitro——
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In Vivo——
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SynonymsOPC-13340
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorAutophagy| mTORC1
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Research Area——
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Indication——
Chemical Information
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CAS Number99522-79-9
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Formula Weight448.475
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Molecular FormulaC25H24N2O6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 270 mg/mL (602.05 mM)
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SMILESCOC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OC\C=C\c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Laraia L, et al. The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nat Chem Biol. 2019 Jul;15(7):710-720.
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