Methoprene

CAS No. 40596-69-8

Methoprene( ZR-515 )

Catalog No. M26753 CAS No. 40596-69-8

Methoprene is a juvenile hormone (JH) mimic and a biological pesticide.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 48 In Stock
10MG 29 In Stock
25MG 45 In Stock
50MG 63 In Stock
100MG 79 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Methoprene
  • Note
    Research use only, not for human use.
  • Brief Description
    Methoprene is a juvenile hormone (JH) mimic and a biological pesticide.
  • Description
    Methoprene is a juvenile hormone (JH) mimic and a biological pesticide. Methoprene acts as an insect growth regulator interfering with the lifecycles of insects and preventing insects from reaching maturity or reproducing.(In Vivo):The time of first brood deposition is affected by methoprene, with a clear concentration-dependent response and a NOEC of 32 nM. Methoprene reduces fecundity according to a 2-segmented line, with thresholds of 24 and < or =0.18 nM. Methoprene reduces the growth rate of daphnids with evidence of only a single concentration-response line, having a threshold of 12.6 nM. Molt frequency is reduced by methoprene in a concentration-dependent manner, with a response curve corresponding to a 2-segmented line and thresholds at 4.2 and 0.21 nM.
  • In Vitro
    Methoprene reduces the growth rate of daphnids with evidence of only a single concentration-response line, having a threshold of 12.6 nM. Molt frequency is reduced by methoprene in a concentration-dependent manner, with a response curve corresponding to a 2-segmented line and thresholds at 4.2 and 0.21 nM. An endpoint related to reproductive maturation, the time of first brood deposition, is also affected by methoprene, with a clear concentration-dependent response and a NOEC of 32 nM. Methoprene reduces fecundity according to a 2-segmented line, with thresholds of 24 and < or =0.18 nM. Methoprene elicits significant toxicity to endocrine-related processes in the 5-50 nM concentration range.
  • In Vivo
    ——
  • Synonyms
    ZR-515
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    E3 Ligase Ligand-Linker Conjugate
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    40596-69-8
  • Formula Weight
    310.478
  • Molecular Formula
    C19H34O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?Ethanol : 100 mg/mL (322.09 m)
  • SMILES
    COC(C)(C)CCCC(C)C\C=C\C(\C)=C\C(=O)OC(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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