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GLN-1062
CAS No. 224169-27-1
GLN-1062( Memogain )
Catalog No. M26751 CAS No. 224169-27-1
GLN-1062 is a pro-drug of galantamine and liberates galantamine on cleavage by a carboxyesterase in the brain.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 57 | In Stock |
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| 2MG | 31 | In Stock |
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| 5MG | 51 | In Stock |
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| 10MG | 79 | In Stock |
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| 25MG | 159 | In Stock |
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| 50MG | 242 | In Stock |
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| 100MG | 339 | In Stock |
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| 200MG | 468 | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameGLN-1062
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NoteResearch use only, not for human use.
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Brief DescriptionGLN-1062 is a pro-drug of galantamine and liberates galantamine on cleavage by a carboxyesterase in the brain.
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DescriptionGLN-1062 is a pro-drug of galantamine and liberates galantamine on cleavage by a carboxyesterase in the brain.(In Vivo):GLN-1062 has more than 15-fold higher bioavailability in the brain than the same doses of galantamine. In animal models of drug-induced amnesia, GLN-1062 produced several fold larger cognitive improvement than the same doses of galantamine, without exhibiting any significant levels of gastrointestinal side effects that are typical for the unmodified drug and other inhibitors of cholinesterases, such as donepezil and rivastigmin. In the ferret, dramatically reduced emetic and behavioral responses were observed when GLN-1062 was administered instead of galantamine.
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In Vitro——
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In Vivo——
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SynonymsMemogain
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PathwayOthers
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TargetOther Targets
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RecptorFarnesyl transferase (FTase)
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Research Area——
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Indication——
Chemical Information
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CAS Number224169-27-1
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Formula Weight391.467
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Molecular FormulaC24H25NO4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (255.45 mM)
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SMILES[H][C@]12C[C@@H](OC(=O)c3ccccc3)C=C[C@]11CCN(C)Cc3ccc(OC)c(O2)c13
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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MYCOPHENOLATE SODIUM
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