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Imirestat
CAS No. 89391-50-4
Imirestat( AL 1576 | Alcon 1576 | HOE 843 )
Catalog No. M26715 CAS No. 89391-50-4
Imirestat is an aldose reductase inhibitor that can be used in diabetes research.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 49 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 46 | In Stock |
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| 10MG | 71 | In Stock |
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| 25MG | 143 | In Stock |
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| 50MG | 226 | In Stock |
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| 100MG | 362 | In Stock |
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| 200MG | 514 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameImirestat
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NoteResearch use only, not for human use.
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Brief DescriptionImirestat is an aldose reductase inhibitor that can be used in diabetes research.
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DescriptionImirestat is an aldose reductase inhibitor that can be used in diabetes research.(In Vivo):Administration of 1 mg/kg Imirestat increased nerve conduction velocity, however, had no effect on resistance to hypoxic conduction block or deficits in insulin-stimulated Uban-sensitive ATPase activity.
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In Vitro——
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In VivoImirestat (1 mg/kg) improves nerve conduction velocity but is without effect upon the resistance to hypoxic conduction blockade or the deficit in insulin-stimulated oubain-sensitive ATPase activity.
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SynonymsAL 1576 | Alcon 1576 | HOE 843
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PathwayEndocrinology/Hormones
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TargetReductase
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RecptorSIRT1
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Research Area——
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Indication——
Chemical Information
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CAS Number89391-50-4
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Formula Weight286.238
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Molecular FormulaC15H8F2N2O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 83.33 mg/mL (291.13 mM)
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SMILESFc1ccc2-c3ccc(F)cc3C3(NC(=O)NC3=O)c2c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Napper AD, et al. Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. J Med Chem. 2005 Dec 15;48(25):8045-54.
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