Cart
sales@molnova.com
Ertugliflozin L-pyroglutamic acid
CAS No. 1210344-83-4
Ertugliflozin L-pyroglutamic acid( PF-04971729 L-pyroglutamic acid )
Catalog No. M26680 CAS No. 1210344-83-4
Ertugliflozin L-pyroglutamic acid is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 46 | In Stock |
|
| 5MG | 37 | In Stock |
|
| 10MG | 52 | In Stock |
|
| 25MG | 78 | In Stock |
|
| 50MG | 90 | In Stock |
|
| 100MG | 133 | In Stock |
|
| 200MG | 194 | In Stock |
|
| 500MG | 333 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameErtugliflozin L-pyroglutamic acid
-
NoteResearch use only, not for human use.
-
Brief DescriptionErtugliflozin L-pyroglutamic acid is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM.
-
DescriptionErtugliflozin L-pyroglutamic acid is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM. Ertugliflozin L-pyroglutamic acid can be used for studies about the treatment of type 2 diabetes mellitus.(In Vitro):Ertugliflozin L-pyroglutamic acid demonstrated >2000-fold selectivity for SGLT2 over SGLT.(In Vivo):The oral administration of Ertugliflozin L-pyroglutamic to rats acid showed concentration-dependent glucosuria.
-
In Vitro——
-
In Vivo——
-
SynonymsPF-04971729 L-pyroglutamic acid
-
PathwayOthers
-
TargetOther Targets
-
RecptorCaspase-3
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1210344-83-4
-
Formula Weight566
-
Molecular FormulaC27H32ClNO10
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : ≥ 125 mg/mL (220.85 mM)
-
SMILESOC(=O)[C@@H]1CCC(=O)N1.CCOc1ccc(Cc2cc(ccc2Cl)[C@]23OC[C@](CO)(O2)[C@@H](O)[C@H](O)[C@H]3O)cc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Kravchenko DV, et al. Synthesis and structure-activity relationship of 4-substituted 2-(2-acetyloxyethyl)-8-(morpholine-4-sulfonyl)pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors. J Med Chem. 2005 Jun 2;48(11):3680-3.
molnova catalog
related products
-
Swertiachoside B
Swertiachoside B
-
Butyrospermol
Butyrospermol is a protolimonoid extracted from shea (Euphorbia). As a long-chain fatty acid ester first discovered from natural products, Butyrospermol has antifeedant and antitumor activities.
-
Acetylcimigenol 3-O-...
Acetylshengmanol Arabinoside is isolated from Cimicifugae rhizoma.
