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SGN-2FF
CAS No. 2089647-47-0
SGN-2FF( —— )
Catalog No. M26438 CAS No. 2089647-47-0
SGN-2FF is an oral fucosyltransferase inhibitor with antitumor activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 170 | In Stock |
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| 5MG | 155 | In Stock |
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| 10MG | 275 | In Stock |
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| 25MG | 534 | In Stock |
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| 50MG | 732 | In Stock |
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| 100MG | 1014 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSGN-2FF
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NoteResearch use only, not for human use.
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Brief DescriptionSGN-2FF is an oral fucosyltransferase inhibitor with antitumor activity.
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DescriptionSGN-2FF is an oral fucosyltransferase inhibitor with antitumor activity.(In Vitro):SGN-2FF is a fucosylation inhibitor, SGN-2FF inhibits cellular fucosylation by depleting the fucosylation substrate GDP-fucose, and by direct inhibition of fucosyltransferases, and leads to the production of fucosylated glycoproteins including antibodies. SGN-2FF activates human T cells in an antigen-dependent manner.(In Vivo):In multiple mouse tumor models, SGN-2FF exhibits antitumor activity. SGN-2FF shows substantial tumor growth delay. SGN-2FF elevates the protective effect of a lymphoma vaccine in a syngeneic mouse model.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorTelomerase
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Research Area——
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Indication——
Chemical Information
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CAS Number2089647-47-0
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Formula Weight166.148
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Molecular FormulaC6H11FO4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (300.93 mM)
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SMILESC[C@@H]1OC(O)[C@@H](F)[C@H](O)[C@@H]1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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17-Diaminoheptane
17-Diaminoheptane is a chemical compound.
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(S,R,S)-AHPC-PEG4-N3
(S,R,S)-AHPC-PEG4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.
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Cltrinin
Citrinin (NSC 186) is a mycotoxin that causes food contamination and has different toxic effects. Citrinin is an effective oral anticancer agent. Citrinin has various regulatory effects on mouse immune system, including regulating the number of immune cells, inducing apoptosis and autophagy of immune cells, altering toll-like receptor expression and cytokine production. Citrinin can induce oxidative stress and lead to early apoptosis of oocytes. Low doses of Citrinin have neuroprotective effects against glutamate-induced excitotoxicity in rat cortical neurons. In addition, Citrinin also has antibacterial activity.
