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S1PR1 modulator 1
CAS No. 2328109-05-1
S1PR1 modulator 1( —— )
Catalog No. M26430 CAS No. 2328109-05-1
S1PR1 modulator 1 is a selective inhibitor of S1PR1 with a pIC50 of 7.6.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 131 | In Stock |
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| 5MG | 113 | In Stock |
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| 10MG | 164 | In Stock |
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| 25MG | 271 | In Stock |
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| 50MG | 392 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameS1PR1 modulator 1
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NoteResearch use only, not for human use.
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Brief DescriptionS1PR1 modulator 1 is a selective inhibitor of S1PR1 with a pIC50 of 7.6.
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DescriptionS1PR1 modulator 1 is a selective inhibitor of S1PR1 with a pIC50 of 7.6.(In Vitro):S1PR1 modulator 1 shows >40- and >80-fold selectivity, over the other S1PR isoforms S1PR3 (pIC50, 6), S1PR2 and S1PR4 (pIC50s, <5).
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In VitroS1PR1 modulator 1 (Compound 10a; (Z,Z)-10a) is selective at S1PR1 over S1PR3 (pIC50, 6), S1PR2 and S1PR4 (pIC50s, <5).
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorFungal| glucan synthase
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Research Area——
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Indication——
Chemical Information
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CAS Number2328109-05-1
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Formula Weight408.51
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Molecular FormulaC23H24N2O3S
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Purity>98% (HPLC)
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Solubility——
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SMILESN(\CCC)=C\1/N(C(=O)\C(=C\C2=CC(C)=C(OC(C)=O)C=C2)\S1)C3=C(C)C=CC=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Miesel L, et al. Efficacy of Rezafungin in Prophylactic Mouse Models of Invasive Candidiasis, Aspergillosis, and Pneumocystis Pneumonia. Antimicrob Agents Chemother. 2021 Feb 17;65(3):e01992-20.
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