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(Rac)-AMG8379
CAS No. 1641574-26-6
(Rac)-AMG8379( (Rac)-AMG8380 )
Catalog No. M26409 CAS No. 1641574-26-6
(Rac)-AMG8379 is a racemate of AMG8379. AMG8379 is a potent, orally active and selective sulfonamide NaV1.7 antagonist(hNaV1.7 and mNaV1.7 with IC50s of 8.5 and 18.6 nM , respectively ).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 540 | In Stock |
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| 2MG | 278 | In Stock |
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| 5MG | 426 | In Stock |
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| 10MG | 625 | In Stock |
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| 25MG | 938 | In Stock |
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| 50MG | 1283 | In Stock |
|
| 100MG | 1758 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 3515 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name(Rac)-AMG8379
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NoteResearch use only, not for human use.
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Brief Description(Rac)-AMG8379 is a racemate of AMG8379. AMG8379 is a potent, orally active and selective sulfonamide NaV1.7 antagonist(hNaV1.7 and mNaV1.7 with IC50s of 8.5 and 18.6 nM , respectively ).
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Description(Rac)-AMG8379 is a racemate of AMG8379. AMG8379 is a potent, orally active and selective sulfonamide NaV1.7 antagonist(hNaV1.7 and mNaV1.7 with IC50s of 8.5 and 18.6 nM , respectively ).
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In Vitro——
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In Vivo——
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Synonyms(Rac)-AMG8380
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PathwayOthers
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TargetOther Targets
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RecptorATF4| ATF6| ERK| GRP78| MMP
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Research Area——
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Indication——
Chemical Information
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CAS Number1641574-26-6
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Formula Weight543.93
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Molecular FormulaC25H16ClF2N3O5S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=S(NC1=NOC=C1)(C2=CC(C=CC(N3C4=CC(F)=C(C=C4OC)C5=CC(Cl)=CC(F)=C5)=O)=C3C=C2)=O.[Racemate]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zhang B, Han H, et al. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. Biochem Pharmacol. 2016 Mar 15;104:8-18.
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