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Pentiapine
CAS No. 81382-51-6
Pentiapine( CGS 10746 )
Catalog No. M26364 CAS No. 81382-51-6
Pentiapine is a novel inhibitor of dopamine release.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 938 | In Stock |
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| 5MG | 753 | In Stock |
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| 10MG | 1216 | In Stock |
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| 25MG | 1691 | In Stock |
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| 50MG | 2213 | In Stock |
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| 100MG | 3004 | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NamePentiapine
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NoteResearch use only, not for human use.
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Brief DescriptionPentiapine is a novel inhibitor of dopamine release.
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DescriptionPentiapine is a novel inhibitor of dopamine release. (In Vivo):Pentiapine dose-dependently reduces motor activity of mice. Pentiapine dose-dependently reduces morphine-induced hyperactivity. Newman-Keuls post-hoc comparisons indicate that the group receiving morphine plus saline presents more activity than the groups receiving morphine plus 2 (P<0.05), 4, 8, 16, 24 and 32 (P<0.01) mg/kg of Pentiapine. Moreover, the groups receiving morphine plus 0.5, 1 and 2 mg/kg of Pentiapine present more activity than the groups receiving morphine plus 4, 8, 16, 24 and 32 mg/kg of Pentiapine (P<0.01). 30 mg/kg dose of Pentiapine completely blocks the methylenedioxymethamphetamine (MDMA) conditioned place preference (CPP) and also blocks the establishment of a cocaine CPP.
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In Vitro——
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In VivoPentiapine is a novel dopamine release inhibitor.The results show that Pentiapine dose-dependently reduces motor activity of mice. Moreover, Pentiapine dose-dependently reduces morphine-induced hyperactivity. Newman-Keuls post-hoc comparisons indicate that the group receiving morphine plus saline presents more activity than the groups receiving morphine plus 2 (P<0.05), 4, 8, 16, 24 and 32 (P<0.01) mg/kg of Pentiapine. Moreover, the groups receiving morphine plus 0.5, 1 and 2 mg/kg of Pentiapine present more activity than the groups receiving morphine plus 4, 8, 16, 24 and 32 mg/kg of Pentiapine (P<0.01). 30 mg/kg dose of Pentiapine completely blocks the methylenedioxymethamphetamine (MDMA) conditioned place preference (CPP) and also blocks the establishment of a cocaine CPP.
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SynonymsCGS 10746
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PathwayGPCR/G Protein
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TargetDopamine Receptor
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RecptorH1 receptor| H2 receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number81382-51-6
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Formula Weight299.4
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Molecular FormulaC15H17N5S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (334.01 mM)
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SMILESCN1CCN(CC1)C1=Nc2ccccc2Sc2nccn12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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MLS1547
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