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CHMFL-KIT-033

CAS No. 2351801-41-5

CHMFL-KIT-033( —— )

Catalog No. M26113 CAS No. 2351801-41-5

CHMFL-KIT-033 is a potent and selective inhibitor of the c-KIT T670I mutant (IC50: 0.045 μM) for gastrointestinal stromal tumors (GISTs).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

CHMFL-KIT-033
Note

Research use only, not for human use.
Brief Description

CHMFL-KIT-033 is a potent and selective inhibitor of the c-KIT T670I mutant (IC50: 0.045 μM) for gastrointestinal stromal tumors (GISTs).
Description

CHMFL-KIT-033 is a potent and selective inhibitor of the c-KIT T670I mutant (IC50: 0.045 μM) for gastrointestinal stromal tumors (GISTs).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Reactive Oxygen Species
Research Area

——
Indication

——

Chemical Information

CAS Number

2351801-41-5
Formula Weight

415.428
Molecular Formula

C23H18FN5O2
Purity

>98% (HPLC)
Solubility

——
SMILES

Fc1cccc(NC(=O)CC(=O)Nc2ccc3c(\C=C\c4ccccn4)n[nH]c3c2)c1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Floresta G, et al. Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis. Bioorg Chem. 2018 Dec;81:334-339.

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