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Antitrypanosomal agent 1

CAS No. 75144-12-6

Antitrypanosomal agent 1( —— )

Catalog No. M26057 CAS No. 75144-12-6

Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	48	In Stock
25MG	35	In Stock
50MG	49	In Stock
100MG	71	In Stock
200MG	Get Quote	In Stock
500MG	170	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Antitrypanosomal agent 1
Note

Research use only, not for human use.
Brief Description

Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM).
Description

Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM). Antitrypanosomal agent 1 inhibits glutathione reductase (IC50: 64.8 μM) and T. brucei (EC50: 1 μM).
In Vitro

Antitrypanosomal agent 1 (compound 8a) has an selectivity for TR (GR IC50/TR IC50) of 20.
In Vivo

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Synonyms

——
Pathway

Microbiology/Virology
Target

Parasite
Recptor

——
Research Area

——
Indication

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Chemical Information

CAS Number

75144-12-6
Formula Weight

282.59
Molecular Formula

C11H14Cl3NO
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 25 mg/mL (88.47 mM)
SMILES

Cl.CN(C)CCC(=O)c1ccc(Cl)c(Cl)c1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Aranya Manosroi, et al. Melanogenesis of methyl myristate loaded niosomes in B16F10 melanoma cells. J Biomed Nanotechnol. 2013 Apr;9(4):626-38.

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