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ML251
CAS No. 1486482-16-9
ML251( ML251? )
Catalog No. M26000 CAS No. 1486482-16-9
ML251 is a potent novel nanomolar inhibitor of T. brucei and T. cruzi phosphofructokinase.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 301 | In Stock |
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| 5MG | 275 | In Stock |
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| 10MG | 432 | In Stock |
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| 25MG | 715 | In Stock |
|
| 50MG | 986 | In Stock |
|
| 100MG | 1330 | In Stock |
|
| 200MG | 1786 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameML251
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NoteResearch use only, not for human use.
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Brief DescriptionML251 is a potent novel nanomolar inhibitor of T. brucei and T. cruzi phosphofructokinase.
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DescriptionML251 is a potent novel nanomolar inhibitor of T. brucei and T. cruzi phosphofructokinase. ML251 inhibits T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for the research of parasite.(In Vitro):ML251 produces modest dose-dependent toxicity.
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In VitroML251 (T. brucei; 0~33.3 μg/mL) produces modest dose-dependent toxicity. Cell Cytotoxicity Assay Cell Line:T. brucei Concentration:0~33.3 μg/mL Incubation Time:Result:Dose-dependent reduction of cell viability.
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In Vivo——
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SynonymsML251?
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetGlucokinase
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Recptorp53
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Research Area——
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Indication——
Chemical Information
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CAS Number1486482-16-9
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Formula Weight426.27
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Molecular FormulaC17H13Cl2N3O4S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (586.48 mM)
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SMILESO=C(Cc(cc1)cc(Cl)c1Cl)Nc(cc1)ccc1S(Nc1nocc1)(=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Pluquet O, et al. The cytoprotective aminothiol WR1065 activates p53 through a non-genotoxic signaling pathway involving c-Jun N-terminal kinase. J Biol Chem. 2003 Apr 4;278(14):11879-87.
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