Cart
sales@molnova.com
Home - Products - Apoptosis - TNF - Mogroside IIIe

Mogroside IIIe

CAS No. 88901-37-5

Mogroside IIIe( —— )

Catalog No. M24911 CAS No. 88901-37-5

Mogroside III-E is a cucurbitane-type compound isolated from Siraitia grosvenorii, has anti-inflammatory activity, it attenuates LPS-induced acute lung injury in mice partly through regulation of the TLR4/MAPK/NF-κB axis via AMPK activation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 174 In Stock
5MG 93 In Stock
10MG 155 In Stock
25MG 297 In Stock
50MG 434 In Stock
100MG 622 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Mogroside IIIe
  • Note
    Research use only, not for human use.
  • Brief Description
    Mogroside III-E is a cucurbitane-type compound isolated from Siraitia grosvenorii, has anti-inflammatory activity, it attenuates LPS-induced acute lung injury in mice partly through regulation of the TLR4/MAPK/NF-κB axis via AMPK activation.
  • Description
    Mogroside III-E is a cucurbitane-type compound isolated from Siraitia grosvenorii, has anti-inflammatory activity, it attenuates LPS-induced acute lung injury in mice partly through regulation of the TLR4/MAPK/NF-κB axis via AMPK activation. It also has anti-fibrotic activity, it reduces pulmonary fibrosis through Toll-Like receptor 4 pathways.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    TNF
  • Recptor
    TNF-α|IL Receptor|TLR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    88901-37-5
  • Formula Weight
    963.15
  • Molecular Formula
    C48H82O19
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    C[C@]12[C@](CC=C3[C@@]2([H])CC[C@H](O[C@]4([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)CO)C3(C)C)([H])[C@]5([C@@](C)([C@]([C@H](C)CC[C@H](C(C)(O)C)O[C@H]6[C@@H]([C@H]([C@H](O)[C@@H](CO)O6)O)O[C@]7([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]7O)CO)([H])CC5)C[C@H]1O)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Xue W , Mao J , Chen Q , et al. Mogroside IIIE Alleviates High Glucose-Induced Inflammation, Oxidative Stress and Apoptosis of Podocytes by the Activation of AMPK/SIRT1 Signaling Pathway[J]. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 2020, Volume 13:3821-3830.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • bruceine B

    Bruceine B a potent inhibitor of leukocyte-endothelial cell adhesion may have anti-inflammatory activity it can inhibit neutrophil adhesion to lipopolysaccharide-stimulated HUVEC and T cell adhesion to TNF-stimulated HUVEC.?

  • Cucurbitacin IIA

    Cucurbitacin IIA can induce apoptosis and enhance autophagy, contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases.

  • 3,5-Dicaffeoyl-epi-q...

    3,5-Dicaffeoyl-epi-quinic acid can be extracted from Chrysanthemum morifolium. 3,5-Dicaffeoyl-epi-quinic acid has antioxidant activities. 3,5-Dicaffeoyl-epi-quinic acid can scavenge DPPH radical and superoxide anion radical, with IC50s of 5.6 and 2.9 μg/mL respectively.

Sign In Join Free