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SYR127063
CAS No. 871026-18-5
SYR127063( BDBM92454 )
Catalog No. M24884 CAS No. 871026-18-5
SYR127063 (BDBM92454) is a potent and selective HER2 inhibitor, binds to HER2 in a reactive conformation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 272 | In Stock |
|
| 10MG | 408 | In Stock |
|
| 25MG | 672 | In Stock |
|
| 50MG | 945 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSYR127063
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NoteResearch use only, not for human use.
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Brief DescriptionSYR127063 (BDBM92454) is a potent and selective HER2 inhibitor, binds to HER2 in a reactive conformation.
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DescriptionSYR127063 (BDBM92454) is a potent and selective HER2 inhibitor, binds to HER2 in a reactive conformation.
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In Vitro——
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In Vivo——
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SynonymsBDBM92454
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PathwayAngiogenesis
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TargetHER/HSP
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RecptorHER2/HER4/EGFR
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Research Area——
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Indication——
Chemical Information
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CAS Number871026-18-5
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Formula Weight492.88
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Molecular FormulaC23H20ClF3N4O3
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Purity>98% (HPLC)
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SolubilityDMSO:Soluble; Water: Insoluble
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SMILESOCCOCCn(cc1)c2c1ncnc2Nc(cc1)cc(Cl)c1Oc1cc(C(F)(F)F)ccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Aertgeerts K, et al. Structural analysis of the mechanism of inhibition and allosteric activation of the kinase domain of HER2 protein. J Biol Chem. 2011 May 27;286(21):18756-65.
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