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TG 100572 Hydrochloride

CAS No. 867331-64-4

TG 100572 Hydrochloride( —— )

Catalog No. M24874 CAS No. 867331-64-4

TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    TG 100572 Hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases.
  • Description
    TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    VEGFR
  • Recptor
    VEGFR1|VEGFR2|FGFR1|FGFR2|PDGFRβ
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    867331-64-4
  • Formula Weight
    512.43
  • Molecular Formula
    C26H27Cl2N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 20 mg/mL?(39.03 mM;?Need ultrasonic)
  • SMILES
    ClC1=CC=C(O)C=C1C2=CC(C)=C(N=C(NC(C=C3)=CC=C3OCCN4CCCC4)N=N5)C5=C2.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Doukas J, et al. Topical administration of a multi-targeted kinase inhibitor suppresses choroidal neovascularization and retinal edema. J Cell Physiol. 2008 Jul;216(1):29-37.
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