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GW280264X
CAS No. 866924-39-2
GW280264X( Carbamic acid )
Catalog No. M24871 CAS No. 866924-39-2
GW280264X is an inhibitor of ADAM17.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 427 | In Stock |
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| 5MG | 337 | In Stock |
|
| 10MG | 503 | In Stock |
|
| 25MG | 816 | In Stock |
|
| 50MG | 1097 | In Stock |
|
| 100MG | 1479 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGW280264X
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NoteResearch use only, not for human use.
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Brief DescriptionGW280264X is an inhibitor of ADAM17.
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DescriptionGW280264X is an inhibitor of ADAM17 .
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In VitroCell Viability Assay Cell Line:Glioblastoma-initiating cells (GIC) GS-7 cells Concentration:0.1, 1, and 3 μM Incubation Time:48 hours Result:Proliferation of GIC is inhibited through inhibition of ADAM10 and ADAM17.
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In VivoAnimal Model:C57BL/6 miceDosage:100 ?μg/kg Administration:I.p. injected; every day for one week starting 4?h post-surgery Result:Showed significantly improved functional recovery compared to the control group.
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SynonymsCarbamic acid
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PathwayOthers
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TargetOther Targets
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RecptorADAM17
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Research Area——
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Indication——
Chemical Information
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CAS Number866924-39-2
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Formula Weight575.72
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Molecular FormulaC28H41N5O6S
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESCCC[C@@H]([C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(=O)OCC1=CC=CC=C1)C(=O)NC2=NC=CS2)N(C=O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Malemud C J . Inhibition of MMPs and ADAM/ADAMTS[J]. Biochemical Pharmacology, 2019.
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