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PRX-08066

CAS No. 866206-54-4

PRX-08066( —— )

Catalog No. M24869 CAS No. 866206-54-4

PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that induces selective vasodilation of pulmonary arteries.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 107 In Stock
5MG 116 In Stock
10MG 169 In Stock
25MG 351 In Stock
50MG 511 In Stock
100MG 733 In Stock
200MG 1004 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    PRX-08066
  • Note
    Research use only, not for human use.
  • Brief Description
    PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that induces selective vasodilation of pulmonary arteries.
  • Description
    PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that induces selective vasodilation of pulmonary arteries.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT2B
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    866206-54-4
  • Formula Weight
    401.89
  • Molecular Formula
    C19H17ClFN5S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:7 mg/mL (17.42 mM; Need ultrasonic)
  • SMILES
    C1CN(CCC1NC2=C3C=C(SC3=NC=N2)Cl)CC4=CC(=C(C=C4)F)C#N
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Porvasnik SL, et al. PRX-08066, a novel 5-hydroxytryptamine receptor 2B antagonist, reduces monocrotaline-induced pulmonary arterial hypertension and right ventricular hypertrophy in rats. J Pharmacol Exp Ther. 2010 Aug;334(2):364-72.
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