Cart
sales@molnova.com
McMMAF
CAS No. 863971-19-1
McMMAF( Maleimidocaproyl monomethylauristatin F )
Catalog No. M24863 CAS No. 863971-19-1
McMMAF is a protective group-conjugated MMAF. MMAF is a potent tubulin polymerization inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 116 | In Stock |
|
| 10MG | 187 | In Stock |
|
| 25MG | 432 | In Stock |
|
| 50MG | 592 | In Stock |
|
| 100MG | 770 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameMcMMAF
-
NoteResearch use only, not for human use.
-
Brief DescriptionMcMMAF is a protective group-conjugated MMAF. MMAF is a potent tubulin polymerization inhibitor.
-
DescriptionMcMMAF is a protective group-conjugated MMAF. MMAF is a potent tubulin polymerization inhibitor.It is a MMAF derivative having a Maleimidocaproyl linker (MC linker), which is ready to conjugate to antibody or other proteins or biopolymers. Mafodotin is a useful agent for make antibody drug conjugate (ADC) for targeted drug delivery.
-
In Vitro——
-
In Vivo——
-
SynonymsMaleimidocaproyl monomethylauristatin F
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetMicrotubule/Tubulin
-
Recptortubulin polymerization|Drug-Linker Conjugates for ADC
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number863971-19-1
-
Formula Weight925.16
-
Molecular FormulaC49H76N6O11
-
Purity>98% (HPLC)
-
SolubilityDMSO:100 mg/mL (108.09 mM)
-
SMILESO=C(O)[C@H](CC1=CC=CC=C1)NC([C@H](C)[C@H]([C@H]2N(C(C[C@@H](OC)[C@@H](N(C)C([C@@H](NC([C@@H](N(C)C(CCCCCN3C(C=CC3=O)=O)=O)C(C)C)=O)C(C)C)=O)[C@@H](C)CC)=O)CCC2)OC)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Polson AG, et al. Antibody-drug conjugates for the treatment of non-Hodgkin's lymphoma: target and linker-drug selection. Cancer Res. 2009 Mar 15;69(6):2358-2364.
molnova catalog
related products
-
T-1101 tosylate
T-1101 tosylate is an inhibitor of Hec1/Nek2 with antitumor activity.
-
Valecobulin hydrochl...
Valecobulin hydrochloride is a potent inhibitor of β-tubulin polymerization.
-
Podophyllotoxin
Podophyllotoxin is a lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants.
