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UVI 3003

CAS No. 847239-17-2

UVI 3003( —— )

Catalog No. M24839 CAS No. 847239-17-2

UVI 3003 is a highly selective antagonist of the retinoid X receptor. UVI 3003 inhibits Xenopus and human RXRα in Cos7 cells (IC50s: 0.22 and 0.24 μM, respectively).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 74 In Stock
2MG 42 In Stock
5MG 65 In Stock
10MG 116 In Stock
25MG 242 In Stock
50MG 398 In Stock
100MG 594 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    UVI 3003
  • Note
    Research use only, not for human use.
  • Brief Description
    UVI 3003 is a highly selective antagonist of the retinoid X receptor. UVI 3003 inhibits Xenopus and human RXRα in Cos7 cells (IC50s: 0.22 and 0.24 μM, respectively).
  • Description
    UVI 3003 is a highly selective antagonist of the retinoid X receptor. UVI 3003 inhibits Xenopus and human RXRα in Cos7 cells (IC50s: 0.22 and 0.24 μM, respectively).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    Autophagy|RXRα
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    847239-17-2
  • Formula Weight
    436.58
  • Molecular Formula
    C28H36O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (229.05 mM; Need ultrasonic)
  • SMILES
    CCCCCOC1=C(C2=CC(/C=C/C(O)=O)=CC=C2O)C=C3C(C(C)(CCC3(C)C)C)=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhu J, et al. The unexpected teratogenicity of RXR antagonist UVI3003 via activation of PPARγ in Xenopus tropicalis. Toxicol Appl Pharmacol. 2017 Jan 1;314:91-97.
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