Raloxifene( Pharoxifene | Raloxifenum | Keoxifene | LY-139481 )

Catalog No. M24833 CAS No. 84449-90-1

COA

Datasheet

HNMR

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Product Name

Raloxifene
Note

Research use only, not for human use.
Brief Description

Raloxifene is a selective oestrogen receptor modulator. It has effects on bone and breast cancer and cardiovascular disease risk.
Description

Raloxifene is a selective oestrogen receptor modulator. It has effects on bone and breast cancer and cardiovascular disease risk.
In Vitro

——
In Vivo

Raloxifene (4?mg/kg; intragastrically; daily for 13 weeks) significantly prevents bone loss in ovariectomized (OVX) rats. Animal Model:Female, 12-week-old, Wistar rats (OVX rats) Dosage:4?mg/kg Administration:Intragastrically; daily for 13 weeks Result:Significantly increased the levels of E2 in OVX rats and significantly decreased the levels of BGP.
Synonyms

Pharoxifene | Raloxifenum | Keoxifene | LY-139481
Pathway

Others
Target

Other Targets
Recptor

SERM
Research Area

——
Indication

——

CAS Number

84449-90-1
Formula Weight

473.58
Molecular Formula

C28H27NO4S
Purity

>98% (HPLC)
Solubility

DMSO:90 mg/mL (190.04 mM; Need ultrasonic)；Ethanol:9 mg/mL (19.00 mM; Need ultrasonic)
SMILES

Oc(cc1)ccc1-c1c(C(c(cc2)ccc2OCCN2CCCCC2)=O)c(ccc(O)c2)c2s1
Chemical Name

——

1.Khovidhunkit W, et al. Clinical effects of raloxifene hydrochloride in women. Ann Intern Med. 1999;130(5):431-439.

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