5-Geranoxy-7-methoxycoumarin

Research use only, not for human use.

5-Geranoxy-7-methoxycoumarin shows antifungal activity.

5-Geranoxy-7-methoxycoumarin shows antifungal activity.

5-Geranoxy-7-methoxycoumarin (12.5-200 μM; 24-72 hours) induces a significant inhibition of cell growth in a time-dependent manner in SW480 cells.5-Geranoxy-7-methoxycoumarin (50 μM;48 hours) promotes DNA fragmentation and causes apoptosis through inhibition of the p38 MAPK signaling pathway in SW480 cells.5-Geranoxy-7-methoxycoumarin (50 μM; 24-48 hours) increases the percentage of cells in the sub G1/G0 phase from 5.3% (in control cells) to 18% after 48 h incubation.Cell Proliferation Assay Cell Line:SW480 Concentration:0-20 μM Incubation Time:24, 48 and 72 hours Result:Inhibited cell growth by 67% at 72 hours.Apoptosis Analysis Cell Line:SW480 cells Concentration:50 μM Incubation Time:48 hours Result:Induced cell apoptosis.Cell Cycle Analysis Cell Line:SW480 cells Concentration:50 μM Incubation Time:48 hours Result:Inhibited cell cycle progression in vitro.

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Microbiology/Virology

Antifection

Anti-infection

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7380-39-4

328.4

C20H24O4

>98% (HPLC)

DMSO:10 mM

CC(=CCCC(=CCOC1=CC(=CC2=C1C=CC(=O)O2)OC)C)C

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(-20℃)

With Ice Pack

≥ 2 years