Cart
sales@molnova.com
Miglustat
CAS No. 72599-27-0
Miglustat( N-Butyldeoxynojirimycin | NB-DNJ | OGT918 )
Catalog No. M24736 CAS No. 72599-27-0
Miglustat is an alkylated product of imino sugar deoxynojirimycin.It is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 93 | In Stock |
|
| 5MG | 85 | In Stock |
|
| 10MG | 132 | In Stock |
|
| 25MG | 245 | In Stock |
|
| 50MG | 398 | In Stock |
|
| 100MG | 579 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameMiglustat
-
NoteResearch use only, not for human use.
-
Brief DescriptionMiglustat is an alkylated product of imino sugar deoxynojirimycin.It is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1).
-
DescriptionMiglustat is an alkylated product of imino sugar deoxynojirimycin.It is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1).
-
In Vitro——
-
In VivoAnimal Model:NPC1?/? mice Dosage:0.2?mg/kg Administration:Oral administration; once Result:Was able to rescue synaptic plasticity deficits, to restore ERKs activation and to counteract hyperexcitability.
-
SynonymsN-Butyldeoxynojirimycin | NB-DNJ | OGT918
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number72599-27-0
-
Formula Weight219.28
-
Molecular FormulaC10H21NO4
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mM
-
SMILESO[C@H]1[C@H](O)[C@@H](CO)N(CCCC)C[C@@H]1O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Abian, O., et al., Therapeutic strategies for Gaucher disease: miglustat (NB-DNJ) as a pharmacological chaperone for glucocerebrosidase and the different thermostability of velaglucerase alfa and imiglucerase. Mol Pharm, 2011. 8(6): p. 2390-7.
molnova catalog
related products
-
Trifludimoxazin
Trifludimoxazin is an inhibitor of protoporphyrinogen oxidase and can be used as a herbicide.
-
PZ-II-029
PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.
-
SRI-011381 hydrochlo...
SRI-011381 a new-type agonist of the TGF-beta signaling pathway is utilized in the treatment of Alzheimer's disease.
