Euscaphic acid( —— )

Catalog No. M24506 CAS No. 53155-25-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

Euscaphic acid
Note

Research use only, not for human use.
Brief Description

Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of IKK and MAPKs signal transduction to downregulate NF-κB activations.
Description

Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of IKK and MAPKs signal transduction to downregulate NF-κB activations.
In Vitro

Euscaphic acid induces apoptosis and cell cycle arrest in NPC cells by suppression of the PI3K/AKT/mTOR signaling pathway.
In Vivo

——
Synonyms

——
Pathway

Immunology/Inflammation
Target

NOS
Recptor

LDL|NO Synthase|PGE
Research Area

——
Indication

——

CAS Number

53155-25-2
Formula Weight

488.7
Molecular Formula

C30H48O5
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 250 mg/mL (511.56 mM)
SMILES

C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@@H](O)C(C)(C)C5CC[C@@]34C)C2[C@]1(C)O)C(O)=O
Chemical Name

——

1.Mahmud S A . Anti-Contraction Effects of Euscaphic Acid Isolated from Crataegus azarolus var. aronia L on Rat’s Aortic Smooth Muscle. 2015.

Calculator

molnova catalog