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Pasireotide Acetate

CAS No. 396091-76-2

Pasireotide Acetate( —— )

Catalog No. M24357 CAS No. 396091-76-2

Pasireotide Acetate is a stable cyclohexapeptide somatostatin mimic.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Pasireotide Acetate
  • Note
    Research use only, not for human use.
  • Brief Description
    Pasireotide Acetate is a stable cyclohexapeptide somatostatin mimic.
  • Description
    Pasireotide Acetate is a stable cyclohexapeptide somatostatin mimic.
  • In Vitro
    ——
  • In Vivo
    Animal Model:12 month-old conditional Men1 knockout mice with insulinoma Dosage:160 mg/kg/mouth Administration:S.c. every month for 4 months Result:Decreased the serum insulin from 1.060 μg/L to 0.3653 μg/L and increased the serum glucose from 4.246 mM to 7.122 mM.Significantly reduced the tumor size and increased apoptosis.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    396091-76-2
  • Formula Weight
    1107.26
  • Molecular Formula
    C60H70N10O11
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:Soluble
  • SMILES
    NCCCC[C@@]([H])(/C(O)=N/[C@@]([H])(CC1=CC=C(C=C1)OCC2=CC=CC=C2)/C(O)=N/[C@]3(CC4=CC=CC=C4)[H])/N=C([C@@]([H])(CC5=CNC6=CC=CC=C56)/N=C([C@]([H])(C7=CC=CC=C7)/N=C([C@@]8(C[C@]([H])(CN8C3=O)O/C(O)=N/CCN)[H])\O)\O)\O.CC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Coopmans E C , Muhammad A , Van d L A J , et al. How to Position Pasireotide LAR Treatment in Acromegaly[J]. Journal of Clinical Endocrinology & Metabolism, 2019, 104(6):1978-1988.
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