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Home - Products - Nuclear Receptor/Transcription Factor - Keap1-Nrf2 - 2-tert-Butyl-1,4-benzoquinone

2-tert-Butyl-1,4-benzoquinone

CAS No. 3602-55-9

2-tert-Butyl-1,4-benzoquinone( —— )

Catalog No. M24318 CAS No. 3602-55-9

2-tert-Butyl-1,4-benzoquinone (TBQ), an electrophilic metabolite of butylated hydroxyanisole (BHA), causes activation of Nrf2 together with S-arylation of its negative regulator Keap1 in RAW264.7 cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    2-tert-Butyl-1,4-benzoquinone
  • Note
    Research use only, not for human use.
  • Brief Description
    2-tert-Butyl-1,4-benzoquinone (TBQ), an electrophilic metabolite of butylated hydroxyanisole (BHA), causes activation of Nrf2 together with S-arylation of its negative regulator Keap1 in RAW264.7 cells.
  • Description
    2-tert-Butyl-1,4-benzoquinone (TBQ), an electrophilic metabolite of butylated hydroxyanisole (BHA), causes activation of Nrf2 together with S-arylation of its negative regulator Keap1 in RAW264.7 cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Nuclear Receptor/Transcription Factor
  • Target
    Keap1-Nrf2
  • Recptor
    Nrf2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    3602-55-9
  • Formula Weight
    164.2
  • Molecular Formula
    C10H12O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)(C)C(C(C=C1)=O)=CC1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Abiko Y, Kumagai Y. Interaction of Keap1 modified by 2-tert-butyl-1,4-benzoquinone with GSH: evidence for S-transarylation. Chem Res Toxicol. 2013 Jul 15;26(7):1080-7.
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