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DNA2 inhibitor C5

CAS No. 35973-25-2

DNA2 inhibitor C5( —— )

Catalog No. M24317 CAS No. 35973-25-2

DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 115 In Stock
2MG 73 In Stock
5MG 116 In Stock
10MG 188 In Stock
25MG 432 In Stock
50MG 625 In Stock
100MG 889 In Stock
200MG Get Quote In Stock
500MG 1786 In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    DNA2 inhibitor C5
  • Note
    Research use only, not for human use.
  • Brief Description
    DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM).
  • Description
    DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM). DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    DNA2 nuclease
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    35973-25-2
  • Formula Weight
    234.17
  • Molecular Formula
    C10H6N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:31.25 mg/mL (133.45 mM; Need ultrasonic)
  • SMILES
    O=C(C1=C(O)C2=CC=CC([N+]([O-])=O)=C2N=C1)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Binghui Shen, et al. Dna2 inhibitors for cancer treatment. US20170226063A1.
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