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Mecillinam
CAS No. 32887-01-7
Mecillinam( Amdinocillin | AMDINOCILLIN | Coactin | Penicillin HX | Mecillinamum | Hexacillin )
Catalog No. M24265 CAS No. 32887-01-7
Mecillinam, an extended-spectrum penicillin antibiotic, is considered to be active against Gram-negative bacteria by binding specifically to penicillin-binding protein 2 (PBP2).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 29 | In Stock |
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| 10MG | 33 | In Stock |
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| 25MG | 50 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameMecillinam
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NoteResearch use only, not for human use.
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Brief DescriptionMecillinam, an extended-spectrum penicillin antibiotic, is considered to be active against Gram-negative bacteria by binding specifically to penicillin-binding protein 2 (PBP2).
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DescriptionMecillinam, an extended-spectrum penicillin antibiotic, is considered to be active against Gram-negative bacteria by binding specifically to penicillin-binding protein 2 (PBP2). It is used primarily to treat urinary tract infections and has also been used in the treatment of paratyphoid fever and typhoid.
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In Vitro——
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In VivoAnimal Model:Mecillinam (Amdinocillin, 400 mg per kg) is effective for the treatment of catheterassociated infections at high dosages (400 mg per kg of body weight/d).Dosage:50, 100, 200, and 400 mg per kg. Administration:Intravenously each day in four divided doses over a 72-h period.Result:High dose of 400 mg/kg exhibited significant activity.
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SynonymsAmdinocillin | AMDINOCILLIN | Coactin | Penicillin HX | Mecillinamum | Hexacillin
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorBacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number32887-01-7
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Formula Weight325.43
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Molecular FormulaC15H23N3O3S
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Purity>98% (HPLC)
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SolubilityDMSO:Soluble; Water:Insoluble
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SMILESCC1([C@@H](N2[C@H](S1)[C@@H](C2=O)N=CN3CCCCCC3)C(=O)O)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Thulin E, Sundqvist M, Andersson DI. Amdinocillin (Mecillinam) resistance mutations in clinical isolates and laboratory-selected mutants of Escherichia coli. Antimicrob Agents Chemother. 2015 Mar;59(3):1718-27.
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