D-Isoleucine

CAS No. 319-78-8

D-Isoleucine( (2R,3R)-2-Amino-3-methylpentanoic acid | (R)-Isoleucine )

Catalog No. M24252 CAS No. 319-78-8

D-Isoleucine is a selective activator of Asc-1 antiporter, which enhances long-term potentiation at the hippocampal CA1-CA3 via release of endogenous D-serine.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 37 In Stock
25MG 29 In Stock
50MG 47 In Stock
100MG 74 In Stock
200MG Get Quote In Stock
500MG 166 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    D-Isoleucine
  • Note
    Research use only, not for human use.
  • Brief Description
    D-Isoleucine is a selective activator of Asc-1 antiporter, which enhances long-term potentiation at the hippocampal CA1-CA3 via release of endogenous D-serine.
  • Description
    D-Isoleucine is a selective activator of Asc-1 antiporter, which enhances long-term potentiation at the hippocampal CA1-CA3 via release of endogenous D-serine.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    (2R,3R)-2-Amino-3-methylpentanoic acid | (R)-Isoleucine
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Asc-1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    319-78-8
  • Formula Weight
    131.17
  • Molecular Formula
    C6H13NO2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 6.25 mg/mL (47.65 mM)
  • SMILES
    CC[C@@H](C)[C@H](C(O)=O)N
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Rosenberg D, et, al. Neuronal D-serine and glycine release via the Asc-1 transporter regulates NMDA receptor-dependent synaptic activity. J Neurosci. 2013 Feb 20;33(8):3533-44.
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