O-Nornuciferine

CAS No. 3153-55-7

O-Nornuciferine( —— )

Catalog No. M24249 CAS No. 3153-55-7

O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 179 In Stock
5MG 188 In Stock
10MG 312 In Stock
25MG 524 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    O-Nornuciferine
  • Note
    Research use only, not for human use.
  • Brief Description
    O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.
  • Description
    O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.
  • In Vitro
    O-Nornuciferine has an IC50 of 7.91 μM in vitro hERG blockages measured in HEK293 cells. O-Nornuciferine (100 μM) has 47% hERG channel inhibition in Xenopus oocytes by lotus alkaloids.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    hERG
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    3153-55-7
  • Formula Weight
    281.35
  • Molecular Formula
    C18H19NO2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (177.71 mM)
  • SMILES
    CN(CC1)[C@H](Cc(cccc2)c2-c2c3OC)c2c1cc3O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Human Ether-??-go-go Related Gene (hERG) Channel Blocking Aporphine Alkaloids from Lotus Leaves and Their Quantitative Analysis in Dietary Weight Loss Supplements.J Agric Food Chem. 2015 Jun 17;63(23):5634-9.
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