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Artemisone
CAS No. 255730-18-8
Artemisone( Artemifone | BAY 44-9585 )
Catalog No. M24149 CAS No. 255730-18-8
Artemisone is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains (IC50: 0.83 nM). It also is a potent inhibitor of human CMV.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 107 | In Stock |
|
| 5MG | 98 | In Stock |
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| 10MG | 155 | In Stock |
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| 25MG | 257 | In Stock |
|
| 50MG | 355 | In Stock |
|
| 100MG | 479 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameArtemisone
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NoteResearch use only, not for human use.
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Brief DescriptionArtemisone is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains (IC50: 0.83 nM). It also is a potent inhibitor of human CMV.
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DescriptionArtemisone is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains (IC50: 0.83 nM). It also is a potent inhibitor of human CMV.
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In VitroArtemisone inhibits 3D7 and K1 P. falciparum, with IC50s of 0.88±0.59 and 1.23±0.64 nM, respectively.
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In VivoArtemisone is effectve at inhibiting the parasitaemia in the P. berghei NY susceptible strain, with an ED50 of 9.62 mg/kg via subcutaneous route and 11.67 mg/kg via oral administration.Artemisone (3, 1, 0.3 and 0.1 mg/kg, s.c.) in combination with ohter antimalarials has enhanced effect against the chloroquine-resistant line P. yoelii NS
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SynonymsArtemifone | BAY 44-9585
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PathwayMicrobiology/Virology
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TargetParasite
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RecptorCMV|P. falciparum|Parasite
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Research Area——
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Indication——
Chemical Information
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CAS Number255730-18-8
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Formula Weight401.52
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Molecular FormulaC19H31NO6S
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Purity>98% (HPLC)
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SolubilityDMSO:130 mg/mL (323.77 mM; Need ultrasonic)
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SMILESC[C@H](CC[C@H]1[C@H]2C)[C@H](C3)[C@]11OO[C@@]3(C)CO[C@H]1O[C@H]2N(CC1)CCS1(=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Vivas L, et al. Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo. J Antimicrob Chemother. 2007 Apr;59(4):658-65.
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