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Sulfopin

CAS No. 2451481-08-4

Sulfopin( PIN1-3 )

Catalog No. M24127 CAS No. 2451481-08-4

Sulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 67 In Stock
2MG 38 In Stock
5MG 61 In Stock
10MG 93 In Stock
25MG 211 In Stock
50MG 330 In Stock
100MG 523 In Stock
200MG 728 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Sulfopin
  • Note
    Research use only, not for human use.
  • Brief Description
    Sulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.
  • Description
    Sulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.
  • In Vitro
    Cell Proliferation Assay Cell Line:Kuramochi, MDA-MB-468, NGP, NBL-S, MDA-MB-468 cells Concentration:1, 2.5 μM Incubation Time:4,6, 8 days Result:Showed variation in antiproliferative effects across cancer cell lines Kuramochi, MDA-MB-468, NGP and NBL-S, with the most pronounced sensitivity observed in MDA-MB-468 cells.
  • In Vivo
    ——
  • Synonyms
    PIN1-3
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Pin1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2451481-08-4
  • Formula Weight
    281.8
  • Molecular Formula
    C11H20ClNO3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 90 mg/mL (319.38 mM; Need ultrasonic)
  • SMILES
    O=C(N(CC(C)(C)C)C(CC1)CS1(=O)=O)CCl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Dubiella C , Pinch B J , Koikawa K , et al. Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo[J]. Nature Chemical Biology.
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