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Sulfopin
CAS No. 2451481-08-4
Sulfopin( PIN1-3 )
Catalog No. M24127 CAS No. 2451481-08-4
Sulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 67 | In Stock |
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| 2MG | 38 | In Stock |
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| 5MG | 61 | In Stock |
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| 10MG | 93 | In Stock |
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| 25MG | 211 | In Stock |
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| 50MG | 330 | In Stock |
|
| 100MG | 523 | In Stock |
|
| 200MG | 728 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSulfopin
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NoteResearch use only, not for human use.
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Brief DescriptionSulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.
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DescriptionSulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.
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In VitroCell Proliferation Assay Cell Line:Kuramochi, MDA-MB-468, NGP, NBL-S, MDA-MB-468 cells Concentration:1, 2.5 μM Incubation Time:4,6, 8 days Result:Showed variation in antiproliferative effects across cancer cell lines Kuramochi, MDA-MB-468, NGP and NBL-S, with the most pronounced sensitivity observed in MDA-MB-468 cells.
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In Vivo——
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SynonymsPIN1-3
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PathwayOthers
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TargetOther Targets
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RecptorPin1
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Research Area——
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Indication——
Chemical Information
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CAS Number2451481-08-4
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Formula Weight281.8
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Molecular FormulaC11H20ClNO3S
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Purity>98% (HPLC)
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SolubilityDMSO : 90 mg/mL (319.38 mM; Need ultrasonic)
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SMILESO=C(N(CC(C)(C)C)C(CC1)CS1(=O)=O)CCl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Dubiella C , Pinch B J , Koikawa K , et al. Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo[J]. Nature Chemical Biology.
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