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BPK-29 hydrochloride
CAS No. 2444815-73-8
BPK-29 hydrochloride( —— )
Catalog No. M24126 CAS No. 2444815-73-8
BPK-29 hydrochloride is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein interactions by covalently modifying C274.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 31 | In Stock |
|
| 5MG | 29 | In Stock |
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| 10MG | 51 | In Stock |
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| 25MG | 104 | In Stock |
|
| 50MG | 187 | In Stock |
|
| 100MG | 269 | In Stock |
|
| 200MG | 383 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBPK-29 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionBPK-29 hydrochloride is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein interactions by covalently modifying C274.
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DescriptionBPK-29 hydrochloride is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein interactions by covalently modifying C274. It impairs the anchorage-independent growth of KEAP1-mutant cancer cells.
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In VitroBPK-29 hydrochloride substantially engages NR0B1 with good overall proteomic selectivity in KEAP1-mutant Non-Small Cell Lung Cancers.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number2444815-73-8
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Formula Weight506.46
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Molecular FormulaC26H33Cl2N3O3
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Purity>98% (HPLC)
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SolubilityDMSO:62.5 mg/mL (123.41 mM; Need ultrasonic)
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SMILESC1CC(CCN(C1)C(=O)C2=CC=C(C=C2)N3CCOCC3)N(CC4=CC=CC=C4)C(=O)CCl.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Bar-Peled L, et al. Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer. Cell. 2017 Oct 19;171(3):696-709.e23.
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