Cart
sales@molnova.com
PF-06928215
CAS No. 2378173-15-8
PF-06928215( —— )
Catalog No. M24095 CAS No. 2378173-15-8
PF-06928215 is an inhibitor of cGAS (cyclic GMP-AMP Synthase) (IC50 of 4.9 μΜ).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 188 | In Stock |
|
| 5MG | 180 | In Stock |
|
| 10MG | 264 | In Stock |
|
| 25MG | 502 | In Stock |
|
| 50MG | 715 | In Stock |
|
| 100MG | 1004 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePF-06928215
-
NoteResearch use only, not for human use.
-
Brief DescriptionPF-06928215 is an inhibitor of cGAS (cyclic GMP-AMP Synthase) (IC50 of 4.9 μΜ).
-
DescriptionPF-06928215 is an inhibitor of cGAS (cyclic GMP-AMP Synthase) (IC50 of 4.9 μΜ).
-
In VitroPF-06928215 displays no activity in cellular cGAS assays measuring dsDNA-induced IFN-beta expression.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorcGAS
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2378173-15-8
-
Formula Weight380.4
-
Molecular FormulaC20H20N4O4
-
Purity>98% (HPLC)
-
SolubilityDMSO:33.33 mg/mL (87.62 mM; Need ultrasonic)
-
SMILESOC1=CC(C2=CC=CC=C2)=NC3=C(C(N[C@H]4CCCC[C@H]4C(O)=O)=O)C=NN13
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Hall J, et al. Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay. PLoS One. 2017 Sep 21;12(9):e0184843.
molnova catalog
related products
-
BQ-3020 TFA
BQ-3020 (TFA) is a selective ETB receptor agonist that inhibits [125I] et-1 binding to the ETB receptor in the cerebellum with a 0.2nm IC50, causing vasoconstriction.
-
RSS0680
RSS0680 is a protein kinase degrader that degrades a variety of kinases and can be used to study diseases caused by kinase abnormalities.
-
β-Bag Cell Peptide
β-Bag Cell Peptide
