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Pomalidomide-C2-NH2 hydrochloride

CAS No. 2305369-00-8

Pomalidomide-C2-NH2 hydrochloride( —— )

Catalog No. M24047 CAS No. 2305369-00-8

Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Pomalidomide-C2-NH2 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.
  • Description
    Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PROTACs
  • Target
    E3 Ligase Ligand
  • Recptor
    cereblon (CRBN) E3 ligase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2305369-00-8
  • Formula Weight
    352.77
  • Molecular Formula
    C15H17ClN4O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (354.34 mM)
  • SMILES
    O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCN)=O.[H]Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Shibata N , Nagai K , Morita Y , et al. Development of protein degradation inducers of androgen receptor by conjugation of androgen receptor ligands and inhibitor of apoptosis protein (IAP) ligands[J]. Journal of Medicinal Chemistry, 2017:acs.jmedchem.7b00168.
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