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MARK4 inhibitor 1

CAS No. 2271081-58-2

MARK4 inhibitor 1( —— )

Catalog No. M24033 CAS No. 2271081-58-2

MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis. MARK4 inhibitor 1 is a potent microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 258 In Stock
10MG 376 In Stock
25MG 632 In Stock
50MG 881 In Stock
100MG 1190 In Stock
200MG 1600 In Stock
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Biological Information

  • Product Name
    MARK4 inhibitor 1
  • Note
    Research use only, not for human use.
  • Brief Description
    MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis. MARK4 inhibitor 1 is a potent microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM.
  • Description
    MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis. MARK4 inhibitor 1 is a potent microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM.
  • In Vitro
    Cell Proliferation Assay Cell Line:MCF-7, MDA-MB-435s and HepG2 cells Concentration:0-200 μM Incubation Time:24 and 48 h Result:Decreased the viability of these cells in a concentration dependent manner.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    MARK4
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2271081-58-2
  • Formula Weight
    390.4
  • Molecular Formula
    C20H18N6O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    O=C(C1=CN(CC2=CC=C(OC)C=C2)N=N1)N\N=C3C4=CC=CC(C)=C4NC\3=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Aneja B, et al. Design and development of Isatin-triazole hydrazones as potential inhibitors of microtubule affinity-regulating kinase 4 for the therapeutic management of cell proliferation and metastasis. Eur J Med Chem. 2019 Feb 1;163:840-852.
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