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(-)-(S)-B-973B
CAS No. 2244989-34-0
(-)-(S)-B-973B( —— )
Catalog No. M24024 CAS No. 2244989-34-0
(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 111 | In Stock |
|
| 2MG | 61 | In Stock |
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| 5MG | 101 | In Stock |
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| 10MG | 163 | In Stock |
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| 25MG | 330 | In Stock |
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| 50MG | 500 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name(-)-(S)-B-973B
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NoteResearch use only, not for human use.
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Brief Description(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.
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Description(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetAChR
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Recptorα7 nAChR
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Research Area——
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Indication——
Chemical Information
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CAS Number2244989-34-0
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Formula Weight452.5
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Molecular FormulaC24H26F2N6O
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Purity>98% (HPLC)
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SolubilityDMSO:65 mg/mL (138.33 mM; Need ultrasonic)
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SMILESC[C@@H](c1nc(N(CC2)CCN2c2ncccc2)cnc1)NC(CCc(cc1)cc(F)c1F)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Garai S, et al. B-973, a Novel α7 nAChR Ago-PAM: Racemic and Asymmetric Synthesis, Electrophysiological Studies, and in Vivo Evaluation. ACS Med Chem Lett. 2018 Oct 11;9(11):1144-1148.
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