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AT-007

CAS No. 2170729-29-8

AT-007( —— )

Catalog No. M23983 CAS No. 2170729-29-8

AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	120	In Stock
5MG	107	In Stock
10MG	180	In Stock
25MG	330	In Stock
50MG	523	In Stock
100MG	728	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

AT-007
Note

Research use only, not for human use.
Brief Description

AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM).
Description

AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and prevents disease complications in GALT deficiency rats.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Endocrinology/Hormones
Target

Reductase
Recptor

Aldose Reductase
Research Area

——
Indication

——

Chemical Information

CAS Number

2170729-29-8
Formula Weight

425.4
Molecular Formula

C17H10F3N3O3S2
Purity

>98% (HPLC)
Solubility

DMSO:35.71 mg/mL (83.94 mM; Need ultrasonic)
SMILES

OC(CC(c1cscc11)=NN(Cc2nc(cc(C(F)(F)F)cc3)c3s2)C1=O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Maeve Conneighton, et al. Applied Therapeutics Announces Initiation of Phase 1/2 Study of AT-007 in Galactosemia.

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