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GSK-2894631A
CAS No. 2101626-26-8
GSK-2894631A( HPGDS inhibitor 2 )
Catalog No. M23952 CAS No. 2101626-26-8
HPGDS inhibitor 2 is a potent, selective hematopoietic prostaglandin D synthase (h-pgds) inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 93 | In Stock |
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| 5MG | 86 | In Stock |
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| 10MG | 139 | In Stock |
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| 25MG | 247 | In Stock |
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| 50MG | 310 | In Stock |
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| 100MG | 414 | In Stock |
|
| 200MG | 558 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGSK-2894631A
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NoteResearch use only, not for human use.
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Brief DescriptionHPGDS inhibitor 2 is a potent, selective hematopoietic prostaglandin D synthase (h-pgds) inhibitor.
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DescriptionHPGDS inhibitor 2 is a potent, selective hematopoietic prostaglandin D synthase (h-pgds) inhibitor, IC50 = 9.9 nm.
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In Vitro——
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In Vivo——
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SynonymsHPGDS inhibitor 2
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PathwayImmunology/Inflammation
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TargetPGE synthase
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RecptorhPGDS
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Research Area——
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Indication——
Chemical Information
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CAS Number2101626-26-8
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Formula Weight378.41
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Molecular FormulaC20H24F2N2O3
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Purity>98% (HPLC)
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SolubilityDMSO:130mg/ml(343.54mM)
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SMILESFC(F)OC1=CC=C2C(N=CC(C(N[C@@H]3CC[C@@H](C(C)(C)O)CC3)=O)=C2)=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Rc A , Dnd A , Yd A , et al. The exploration of aza-quinolines as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors with low brain exposure[J]. Bioorganic & Medicinal Chemistry, 2020, 28( 23).
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