Ac-DEVD-AFC
CAS No. 201608-14-2
Ac-DEVD-AFC( —— )
Catalog No. M23904 CAS No. 201608-14-2
Ac-DEVD-AFC is a fluorogenic substrate.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 245 | In Stock |
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| 5MG | 140 | In Stock |
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| 10MG | 263 | In Stock |
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| 25MG | 446 | In Stock |
|
| 50MG | 628 | In Stock |
|
| 100MG | 876 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAc-DEVD-AFC
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NoteResearch use only, not for human use.
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Brief DescriptionAc-DEVD-AFC is a fluorogenic substrate.
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DescriptionAc-DEVD-AFC is a fluorogenic substrate.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number201608-14-2
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Formula Weight729.61
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Molecular FormulaC30H34F3N5O13
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Purity>98% (HPLC)
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SolubilityDMSO: 40 mg/mL?(54.82 mM);H2O: insoluble
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SMILESO=C(O)C[C@@H](C(N)=O)N(C([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@H](CC(O)=O)NC(C)=O)=O)=O)=O)C1=CC=C(C(O2)=C1)C(C(F)(F)F)=CC2=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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PKC ζ pseudosubstrat...
Inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide. Consists of amino acids 113 - 129 of PKC ζ pseudosubstrate domain linked by a disulphide bridge to the Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37°C, ensuring rapid and effective uptake of the inhibitor peptide. Once inside the cell, the disulphide bonds are subjected to reduction in the cytoplasm leading to release of the inhibitor peptide. Induces mast cell degranulation by a PKC ζ-independent pathway.
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