Iclaprim( AR-100 )

Catalog No. M23874 CAS No. 192314-93-5

Iclaprim is a novel specific bacterial Dihydrofolate inhibitor.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Iclaprim
Note

Research use only, not for human use.
Brief Description

Iclaprim is a novel specific bacterial Dihydrofolate inhibitor.
Description

Iclaprim is a novel specific bacterial Dihydrofolate inhibitor. It can inhibit the growth of S. aureus (MIC90: 0.06 μg/mL).(In Vitro):Iclaprim inhibits the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL.
In Vitro

Iclaprim inhibits the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL.
In Vivo

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Synonyms

AR-100
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial|Bacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

192314-93-5
Formula Weight

354.4
Molecular Formula

C19H22N4O3
Purity

>98% (HPLC)
Solubility

DMSO:28 mg/mL (79 mM; Need ultrasonic and warming)
SMILES

COc1cc(Cc2c(N)nc(N)nc2)c(C=CC(C2CC2)O2)c2c1OC
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Schneider P, et al. Iclaprim, a novel diaminopyrimidine with potent activity on trimethoprim sensitive and resistant bacteria. Bioorg Med Chem Lett. 2003 Dec 1;13(23):4217-21.

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